smythfoam

Biology

I currently mainly work on biological applications of machine learning, but I remain a bio-beginner. Biology is obviously a huge topic. Many references here may be too introductory for your tastes. Note that many biology tools are still very R based (see Bioconductor).

The classical canon

A very biased personal take based on MITx 7.00x:

A great review of biology basics by Eric Lander: MITx 7.00x Introduction to Biology - The Secret of Life

and its textbooks:

Searchable version of Alberts et al Molecular Biology of the Cell, 4th edition

Searchable version of Griffiths et al An Introduction to Genetic Analysis, 7th edition

https://www.ebi.ac.uk/training/online/courses/human-genetic-variation-introduction/

https://proteinstructures.com/

MOOCs, books and other tutorials

http://eddylab.org/cupbook.html

Intermediate Genetics https://www.ndsu.edu/pubweb/~mcclean/plsc431/431g.htm

https://www.broadinstitute.org/scientific-community/science/programs/medical-and-population-genetics/primers/primer-medical-and-pop

A guide to machine learning for biologists

CELL BIOLOGY BY THE NUMBERS

https://www.coursera.org/specializations/immunology via a colleague.

Project Rosalind - learn by doing, like Project Euler etc.

Laurent Gatto’s teaching material - very R based.

Machine Learning for Healthcare

Cloud-based Tutorials on Structural Bioinformatics

Modern Statistics for Modern Biology, Susan Holmes Wolfgang Huber, free book.

Introduction to Protein Structure 2nd Edition by Carl Branden (Author), John Tooze (Author)

https://wou.edu/chemistry/courses/online-chemistry-textbooks/ch450-and-ch451-biochemistry-defining-life-at-the-molecular-level/chapter-2-protein-structure/

Jupyter Notebooks for learning the PyRosetta platform for biomolecular structure prediction and design, Gray et al

https://eriqande.github.io/eca-bioinf-handbook/

Church course https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/pages/readings/

EMBl-EBI-SIB Trainings

https://www.ebi.ac.uk/training/

https://www.embl.de/training/e-learning/index.html

https://edu.sib.swiss

Immunology References

Kuby - Immunology

Janeway’s Immunobiology

Podcasts

This week in Virology

Other resources

Meetups

Papers

Deep Learning in Protein Structural Modeling and Design, by Jeff Gray et al. arXiv:2007.08383

A large review article: Opportunities and obstacles for deep learning in biology and medicine

Machine learning for integrating data in biology and medicine: Principles, practice, and opportunities

Survey on Representation Learning for Networks in Biology and Medicine by Zitnik et al: https://arxiv.org/abs/2104.04883

Kevin Yang’s excellent github page on ML for proteins: https://github.com/yangkky/Machine-learning-for-proteins